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Adhesion stimulates Scar/WAVE phosphorylation in mammalian cells

The Scar/WAVE complex catalyzes the protrusion of pseudopods and lamellipods, and is therefore a principal regulator of cell migration. However, it is unclear how its activity is regulated, beyond a dependence on Rac. Phosphorylation of the proline-rich region, by kinases such as Erk2, has been sugg...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Commun Integr Biol
Hauptverfasser: Singh, Shashi Prakash, Insall, Robert H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7781634/
https://ncbi.nlm.nih.gov/pubmed/33447346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420889.2020.1855854
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