Tissue specific diversification, virulence and immune response to Mycobacterium bovis BCG in a patient with an IFN-γ R1 deficiency

Summary: We characterized Mycobacterium bovis BCG isolates found in lung and brain samples from a previously vaccinated patient with IFNγR1 deficiency. The isolates collected displayed distinct genomic and phenotypic features consistent with host adaptation and associated changes in antibiotic susce...

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Detalhes bibliográficos
Publicado no:Virulence
Main Authors: Korol, Cecilia B., Shallom, Shamira J., Arora, Kriti, Boshoff, Helena I., Freeman, Alexandra F., King, Alejandra, Agrawal, Sonia, Daugherty, Sean C., Jancel, Timothy, Kabat, Juraj, Ganesan, Sundar, Torrero, Marina N., Sampaio, Elizabeth P., Barry, Clifton, Holland, Steve M, Tettelin, Hervé, Rosenzweig, Sergio D, Zelazny, Adrian M.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7781554/
https://ncbi.nlm.nih.gov/pubmed/33356838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2020.1848108
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