Clonal Diversification and Changes in Lipid Traits and Colony Morphology in Mycobacterium abscessus Clinical Isolates

The smooth-to-rough colony morphology shift in Mycobacterium abscessus has been implicated in loss of glycopeptidolipid (GPL), increased pathogenicity, and clinical decline in cystic fibrosis (CF) patients. However, the evolutionary phenotypic and genetic changes remain obscure. Serial isolates from...

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Detalhes bibliográficos
Publicado no:J Clin Microbiol
Main Authors: Park, In Kwon, Hsu, Amy P., Tettelin, Hervé, Shallom, Shamira J., Drake, Steven K., Ding, Li, Wu, Un-In, Adamo, Nick, Prevots, D. Rebecca, Olivier, Kenneth N., Holland, Steven M., Sampaio, Elizabeth P., Zelazny, Adrian M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Mycobacteriology and Aerobic Actinomycetes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609687/
https://ncbi.nlm.nih.gov/pubmed/26292297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02015-15
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