Risk Characterization and Probabilistic Concentration–Response Modeling of Complex Environmental Mixtures Using New Approach Methodologies (NAMs) Data from Organotypic in Vitro Human Stem Cell Assays

BACKGROUND: Risk assessment of chemical mixtures or complex substances remains a major methodological challenge due to lack of available hazard or exposure data. Therefore, risk assessors usually infer hazard or risk from data on the subset of constituents with available toxicity values. OBJECTIVES:...

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Vydáno v:Environ Health Perspect
Hlavní autoři: Hsieh, Nan-Hung, Chen, Zunwei, Rusyn, Ivan, Chiu, Weihsueh A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Environmental Health Perspectives 2021
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7781439/
https://ncbi.nlm.nih.gov/pubmed/33395322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP7600
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