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Simvastatin profoundly impairs energy metabolism in primary human muscle cells
OBJECTIVES: Simvastatin use is associated with muscular side effects, and increased risk for type 2 diabetes (T2D). In clinical use, simvastatin is administered in inactive lipophilic lactone-form, which is then converted to active acid-form in the body. Here, we have investigated if lactone- and ac...
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| Publicado no: | Endocr Connect |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Bioscientifica Ltd
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7780958/ https://ncbi.nlm.nih.gov/pubmed/33295884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EC-20-0444 |
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