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Adaptability of the ubiquitin-proteasome system to proteolytic and folding stressors

Aging, disease, and environmental stressors are associated with failures in the ubiquitin-proteasome system (UPS), yet a quantitative understanding of how stressors affect the proteome and how the UPS responds is lacking. Here we assessed UPS performance and adaptability in yeast under stressors usi...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Work, Jeremy J., Brandman, Onn
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780722/
https://ncbi.nlm.nih.gov/pubmed/33382395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201912041
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