LncRNA CRNDE attenuates chemoresistance in gastric cancer via SRSF6-regulated alternative splicing of PICALM

De novo and acquired resistance, which are mainly mediated by genetic alterations, are barriers to effective routine chemotherapy. However, the mechanisms underlying gastric cancer (GC) resistance to chemotherapy are still unclear. We showed that the long noncoding RNA CRNDE was related to the chemo...

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Vydáno v:Mol Cancer
Hlavní autoři: Zhang, Feifei, Wang, Hui, Yu, Jiang, Yao, Xueqing, Yang, Shibin, Li, Weidong, Xu, Lijun, Zhao, Liang
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Letter to the Editor
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780690/
https://ncbi.nlm.nih.gov/pubmed/33397371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-020-01299-y
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