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LncRNA CRNDE attenuates chemoresistance in gastric cancer via SRSF6-regulated alternative splicing of PICALM

De novo and acquired resistance, which are mainly mediated by genetic alterations, are barriers to effective routine chemotherapy. However, the mechanisms underlying gastric cancer (GC) resistance to chemotherapy are still unclear. We showed that the long noncoding RNA CRNDE was related to the chemo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cancer
Hauptverfasser: Zhang, Feifei, Wang, Hui, Yu, Jiang, Yao, Xueqing, Yang, Shibin, Li, Weidong, Xu, Lijun, Zhao, Liang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780690/
https://ncbi.nlm.nih.gov/pubmed/33397371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-020-01299-y
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