CDK13 upregulation-induced formation of the positive feedback loop among circCDK13, miR-212-5p/miR-449a and E2F5 contributes to prostate carcinogenesis

BACKGROUND: Both E2F transcription factor and cyclin-dependent kinases (CDKs), which increase or decrease E2F activity by phosphorylating E2F or its partner, are involved in the control of cell proliferation, and some circRNAs and miRNAs regulate the expression of E2F and CDKs. However, little is kn...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Qi, Jin-Chun, Yang, Zhan, Lin, Tao, Ma, Long, Wang, Ya-Xuan, Zhang, Yong, Gao, Chun-Cheng, Liu, Kai-Long, Li, Wei, Zhao, An-Ning, Shi, Bei, Zhang, Hong, Wang, Dan-Dan, Wang, Xiao-Lu, Wen, Jin-Kun, Qu, Chang-Bao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780414/
https://ncbi.nlm.nih.gov/pubmed/33390186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01814-5
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