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CDK13 upregulation-induced formation of the positive feedback loop among circCDK13, miR-212-5p/miR-449a and E2F5 contributes to prostate carcinogenesis

BACKGROUND: Both E2F transcription factor and cyclin-dependent kinases (CDKs), which increase or decrease E2F activity by phosphorylating E2F or its partner, are involved in the control of cell proliferation, and some circRNAs and miRNAs regulate the expression of E2F and CDKs. However, little is kn...

詳細記述

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書誌詳細
出版年:J Exp Clin Cancer Res
主要な著者: Qi, Jin-Chun, Yang, Zhan, Lin, Tao, Ma, Long, Wang, Ya-Xuan, Zhang, Yong, Gao, Chun-Cheng, Liu, Kai-Long, Li, Wei, Zhao, An-Ning, Shi, Bei, Zhang, Hong, Wang, Dan-Dan, Wang, Xiao-Lu, Wen, Jin-Kun, Qu, Chang-Bao
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780414/
https://ncbi.nlm.nih.gov/pubmed/33390186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01814-5
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