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Bizarre giant cells in human angiosarcoma exhibit chemoresistance and contribute to poor survival outcomes

Giant cells (GC) are a poorly understood subset of tumor cells that have been increasingly recognized as a potential contributor to tumor heterogeneity and treatment resistance. We aimed to characterize the biological and clinical significance of GC in angiosarcoma, an aggressive rare cancer of endo...

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Podrobná bibliografie
Vydáno v:Cancer Sci
Hlavní autoři: Tan, Grace Fangmin, Goh, Shane, Lim, Abner Herbert, Liu, Wei, Lee, Jing Yi, Rajasegaran, Vikneswari, Sam, Xin Xiu, Tay, Timothy Kwang Yong, Selvarajan, Sathiyamoorthy, Ng, Cedric Chuan‐Young, Teh, Bin Tean, Chan, Jason Yongsheng
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780052/
https://ncbi.nlm.nih.gov/pubmed/33164299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14726
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