The Role of Orai1 in Regulating Sarcoplasmic Calcium Release, Mitochondrial Morphology and Function in Myostatin Deficient Skeletal Muscle

In mice a naturally occurring 12-bp deletion in the myostatin gene is considered responsible for the compact phenotype (Mstn(Cmpt–dl1Abc), Cmpt) labeled by a tremendous increase in body weight along with signs of muscle weakness, easier fatigability, decreased Orai1 expression and store operated cal...

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Vydáno v:Front Physiol
Hlavní autoři: Sztretye, Mónika, Singlár, Zoltán, Balogh, Norbert, Kis, Gréta, Szentesi, Péter, Angyal, Ágnes, Balatoni, Ildikó, Csernoch, László, Dienes, Beatrix
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7779810/
https://ncbi.nlm.nih.gov/pubmed/33408641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.601090
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