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Hypermuscular mice with mutation in the myostatin gene display altered calcium signalling
Myostatin, a member of the transforming growth factor β family, is a potent negative regulator of skeletal muscle growth, as myostatin-deficient mice show a great increase in muscle mass. Yet the physical performance of these animals is reduced. As an explanation for this, alterations in the steps i...
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| Главные авторы: | , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Blackwell publishing Ltd
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3961092/ https://ncbi.nlm.nih.gov/pubmed/24445322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.261958 |
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