Proteolysis of Rab32 by Salmonella GtgE induces an inactive GTPase conformation

Rab GTPases are central regulators of intracellular vesicular trafficking. They are frequently targeted by bacterial pathogens through post-translational modifications. Salmonella typhimurium secretes the cysteine protease GtgE during infection, leading to a regioselective proteolytic cleavage of th...

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Vydáno v:iScience
Hlavní autoři: Savitskiy, Sergey, Wachtel, Rudolf, Pourjafar-Dehkordi, Danial, Kang, Hyun-Seo, Trauschke, Vanessa, Lamb, Don C., Sattler, Michael, Zacharias, Martin, Itzen, Aymelt
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7779776/
https://ncbi.nlm.nih.gov/pubmed/33426511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101940
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