Reversal of Endothelial Extracellular Vesicle-Induced Smooth Muscle Phenotype Transition by Hypercholesterolemia Stimulation: Role of NLRP3 Inflammasome Activation

Recent studies reported that vascular endothelial cells (ECs) secrete NLR family pyrin domain-containing 3 (NLRP3) inflammasome products such as interleukin-1β (IL-1β) via extracellular vesicles (EVs) under various pathological conditions. EVs represent one of the critical mechanisms mediating the c...

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Опубликовано в: :Front Cell Dev Biol
Главные авторы: Yuan, Xinxu, Bhat, Owais M., Samidurai, Arun, Das, Anindita, Zhang, Yang, Li, Pin-Lan
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020
Предметы:
Cell and Developmental Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7779768/
https://ncbi.nlm.nih.gov/pubmed/33409276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.597423
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