Pilocarpine-induced seizures associate with modifications of LSD1/CoREST/HDAC1/2 epigenetic complex and repressive chromatin in mice hippocampus

Epilepsy is a neurological disorder of genetic or environmental origin characterized by recurrent spontaneous seizures. A rodent model of temporal lobe epilepsy is induced by a single administration of pilocarpine, a non-selective cholinergic muscarinic receptor agonist. The molecular changes associ...

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Dettagli Bibliografici
Pubblicato in:Biochem Biophys Rep
Autori principali: Noches, Verónica, Rivera, Carlos, González, Marcela P., Merello, Gianluca, Olivares-Costa, Montserrat, Andrés, María Estela
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7779720/
https://ncbi.nlm.nih.gov/pubmed/33426312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2020.100889
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