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Bidirectional Action of Cenicriviroc, a CCR2/CCR5 Antagonist, Results in Alleviation of Pain-Related Behaviors and Potentiation of Opioid Analgesia in Rats With Peripheral Neuropathy

Clinical management of neuropathic pain is unsatisfactory, mainly due to its resistance to the effects of available analgesics, including opioids. Converging evidence indicates the functional interactions between chemokine and opioid receptors and their influence on nociceptive processes. Recent stu...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Kwiatkowski, Klaudia, Pawlik, Katarzyna, Ciapała, Katarzyna, Piotrowska, Anna, Makuch, Wioletta, Mika, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7779470/
https://ncbi.nlm.nih.gov/pubmed/33408720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.615327
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