CCR4 Antagonist (C021) Administration Diminishes Hypersensitivity and Enhances the Analgesic Potency of Morphine and Buprenorphine in a Mouse Model of Neuropathic Pain

Neuropathic pain is a chronic condition that remains a major clinical problem owing to high resistance to available therapy. Recent studies have indicated that chemokine signaling pathways are crucial in the development of painful neuropathy; however, the involvement of CC chemokine receptor 4 (CCR4...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Bogacka, Joanna, Ciapała, Katarzyna, Pawlik, Katarzyna, Kwiatkowski, Klaudia, Dobrogowski, Jan, Przeklasa-Muszynska, Anna, Mika, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7372009/
https://ncbi.nlm.nih.gov/pubmed/32760393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01241
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