Simultaneous quantifications of protein-DNA interactions and transcriptomes in single cells with scDam&T-seq

Protein-DNA interactions are essential to establish cell type-specific chromatin architecture and gene expression. We recently developed scDam&T-seq, a multi-omics method that can simultaneously quantify protein-DNA interactions and the transcriptome in single cells. The method effectively combi...

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Detalhes bibliográficos
Publicado no:Nat Protoc
Main Authors: Markodimitraki, Corina M., Rang, Franka J., Rooijers, Koos, de Vries, Sandra S., Chialastri, Alex, de Luca, Kim L., Lochs, Silke J. A., Mooijman, Dylan, Dey, Siddharth S., Kind, Jop
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7779467/
https://ncbi.nlm.nih.gov/pubmed/32350457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-020-0314-8
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