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The β-Cell Genomic Landscape in T1D: Implications for Disease Pathogenesis

PURPOSE OF REVIEW: Type 1 diabetes (T1D) develops as a consequence of a combination of genetic predisposition and environmental factors. Combined, these events trigger an autoimmune disease that results in progressive loss of pancreatic β cells, leading to insulin deficiency. This article reviews th...

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Udgivet i:Curr Diab Rep
Main Authors: Ramos-Rodríguez, Mireia, Pérez-González, Beatriz, Pasquali, Lorenzo
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2021
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7778620/
https://ncbi.nlm.nih.gov/pubmed/33387073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11892-020-01370-4
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