Genetic Mechanisms Highlight Shared Pathways for the Pathogenesis of Polygenic Type 1 Diabetes and Monogenic Autoimmune Diabetes

PURPOSE OF REVIEW: To highlight pathways important for the development of autoimmune diabetes by investigating shared mechanisms of disease in polygenic and monogenic diabetes. RECENT FINDINGS: Genome-wide association studies have identified 57 genetic risk loci for type 1 diabetes. Progress has bee...

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Bibliographic Details
Published in:Curr Diab Rep
Main Authors: Johnson, Matthew B., Cerosaletti, Karen, Flanagan, Sarah E., Buckner, Jane H.
Format: Artigo
Language:Inglês
Published: Springer US 2019
Subjects:
Pathogenesis of Type 1 Diabetes (A Pugliese and SJ Richardson, Section Editors)
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424922/
https://ncbi.nlm.nih.gov/pubmed/30888520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11892-019-1141-6
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