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Exopolysaccharide defects cause hyper-thymineless death in Escherichia coli via massive loss of chromosomal DNA and cell lysis

Thymineless death in Escherichia coli thyA mutants growing in the absence of thymidine (dT) is preceded by a substantial resistance phase, during which the culture titer remains static, as if the chromosome has to accumulate damage before ultimately failing. Significant chromosomal replication and f...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Rao, T. V. Pritha, Kuzminov, Andrei
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7777189/
https://ncbi.nlm.nih.gov/pubmed/33318216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2012254117
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