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Exopolysaccharide defects cause hyper-thymineless death in Escherichia coli via massive loss of chromosomal DNA and cell lysis

Thymineless death in Escherichia coli thyA mutants growing in the absence of thymidine (dT) is preceded by a substantial resistance phase, during which the culture titer remains static, as if the chromosome has to accumulate damage before ultimately failing. Significant chromosomal replication and f...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Rao, T. V. Pritha, Kuzminov, Andrei
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7777189/
https://ncbi.nlm.nih.gov/pubmed/33318216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2012254117
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