1445. Deciphering the Role of the Y221H Ω-loop Substitution in Pseudomonas-derived Cephalosporinase (PDC) in Cephalosporin Resistance

BACKGROUND: Antimicrobial resistance is a major global health threat. Pseudomonas aeruginosa is a leading cause of nosocomial infections and a key opportunistic pathogen in cystic fibrosis. Multidrug resistant strains are classified as a “serious threat” by the CDC. Pseudomonas-derived cephalosporin...

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Publicat a:Open Forum Infect Dis
Autors principals: Mack, Andrew R, Barnes, Melissa D, Taracila, Magdalena A, Mojica, Maria F, Kumar, Vijay, Rutter, Joseph, van den Akker, Focco, Page, Malcolm, Haider, Shozeb, Bonomo, Robert A
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
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Poster Abstracts
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7776846/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofaa439.1626
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