Adipocytes promote breast tumorigenesis through TAZ-dependent secretion of Resistin

Adipocytes have been implicated in breast tumor growth and stemness maintenance through secreted factors. However, the mechanisms by which these cytokines are regulated during diet-induced obesity and contribute to breast tumorigenesis remain largely unknown. Here we show that transcription cofactor...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Gao, Yuhao, Chen, Xiaosong, He, Qing, Gimple, Ryan C., Liao, Yajin, Wang, Liang, Wu, Rong, Xie, Qi, Rich, Jeremy N., Shen, Kunwei, Yuan, Zengqiang
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7776784/
https://ncbi.nlm.nih.gov/pubmed/33318171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2005950117
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