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ACCOUNTING FOR OVERDISPERSION OF LETHAL LESIONS IN THE LINEAR QUADRATIC MODEL IMPROVES PERFORMANCE AT BOTH HIGH AND LOW RADIATION DOSES

PURPOSE: The linear-quadratic (LQ) model represents a simple and robust approximation for many mechanistically-motivated models of radiation effects. We believe its tendency to overestimate cell killing at high doses derives from the usual assumption that radiogenic lesions are distributed according...

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Publicat a:Int J Radiat Biol
Autors principals: Shuryak, Igor, Cornforth, Michael N.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775901/
https://ncbi.nlm.nih.gov/pubmed/32552223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09553002.2020.1784489
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