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Mechanistic Modeling of Dose and Dose Rate Dependences of Radiation-Induced DNA Double Strand Break Rejoining Kinetics in Saccharomyces cerevisiae
Mechanistic modeling of DNA double strand break (DSB) rejoining is important for quantifying and medically exploiting radiation-induced cytotoxicity (e.g. in cancer radiotherapy). Most radiation-induced DSBs are quickly-rejoinable and are rejoined within the first 1–2 hours after irradiation. Others...
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| Published in: | PLoS One |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4711806/ https://ncbi.nlm.nih.gov/pubmed/26741137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146407 |
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