Anti-CXCR4 Single-Chain Variable Fragment Antibodies Have Anti-Tumor Activity

Monoclonal antibodies (mAbs) are large and have limitations as cancer therapeutics. Human single-chain variable fragment (scFv) is a small antibody as a good alternative. It can easily enter cancer tissues, has no immunogenicity and can be produced in bacteria to decrease the cost. The chemokine rec...

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Detalles Bibliográficos
Publicado en:Front Oncol
Main Authors: Liang, Guang-Quan, Liu, Jing, Zhou, Xiao-Xin, Lin, Ze-Xiong, Chen, Tao, Chen, Guo, Wei, Henry
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775505/
https://ncbi.nlm.nih.gov/pubmed/33392074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.571194
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