Fcγ Receptor IIa (FCGR2A) Polymorphism Is Associated With Severe Respiratory Syncytial Virus Disease in Argentinian Infants

BACKGROUND: Most patients with respiratory syncytial virus (RSV) infection requiring hospitalization have no risk factors for severe disease. Genetic variation in the receptor for the Fc portion of IgG (FcγR) determines their affinity for IgG subclasses driving innate and adaptive antiviral immunity...

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Vydáno v:Front Cell Infect Microbiol
Hlavní autoři: Holgado, María Pía, Raiden, Silvina, Sananez, Inés, Seery, Vanesa, De Lillo, Leonardo, Maldonado, Lucas L., Kamenetzky, Laura, Geffner, Jorge, Arruvito, Lourdes
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Cellular and Infection Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775358/
https://ncbi.nlm.nih.gov/pubmed/33392111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2020.607348
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