Fcγ Receptor IIa (FCGR2A) Polymorphism Is Associated With Severe Respiratory Syncytial Virus Disease in Argentinian Infants

BACKGROUND: Most patients with respiratory syncytial virus (RSV) infection requiring hospitalization have no risk factors for severe disease. Genetic variation in the receptor for the Fc portion of IgG (FcγR) determines their affinity for IgG subclasses driving innate and adaptive antiviral immunity...

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Udgivet i:Front Cell Infect Microbiol
Main Authors: Holgado, María Pía, Raiden, Silvina, Sananez, Inés, Seery, Vanesa, De Lillo, Leonardo, Maldonado, Lucas L., Kamenetzky, Laura, Geffner, Jorge, Arruvito, Lourdes
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Cellular and Infection Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775358/
https://ncbi.nlm.nih.gov/pubmed/33392111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2020.607348
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