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Negative feedback by conserved kinases patterns the degradation of Caenorhabditis elegans Raf in vulval fate patterning
Activation of a canonical EGFR-Ras-Raf-ERK cascade initiates patterning of multipotent vulval precursor cells (VPCs) of Caenorhabditis elegans. We have previously shown that this pathway includes a negative-feedback component in which MPK-1/ERK activity targets the upstream kinase LIN-45/Raf for deg...
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| Publicado no: | Development |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7774884/ https://ncbi.nlm.nih.gov/pubmed/33144396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.195941 |
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