Simultaneous targeting of primary tumor, draining lymph node, and distant metastases through high endothelial venule-targeted delivery

Cancer patients with malignant involvement of tumor-draining lymph nodes (TDLNs) and distant metastases have the poorest prognosis. A drug delivery platform that targets the primary tumor, TDLNs, and metastatic niches simultaneously, remains to be developed. Here, we generated a novel monoclonal ant...

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Veröffentlicht in:Nano Today
Hauptverfasser: Jiang, Liwei, Jung, Sungwook, Zhao, Jing, Kasinath, Vivek, Ichimura, Takaharu, Joseph, John, Fiorina, Paolo, Liss, Andrew S., Shah, Khalid, Annabi, Nasim, Joshi, Nitin, Akama, Tomoya O., Bromberg, Jonathan S., Kobayashi, Motohiro, Uchimura, Kenji, Abdi, Reza
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7774643/
https://ncbi.nlm.nih.gov/pubmed/33391389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nantod.2020.101045
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