Increase in Kelch 13 Polymorphisms in Plasmodium falciparum, Southern Rwanda

Artemisinin resistance in Plasmodium falciparum is associated with nonsynonymous mutations in the Kelch 13 (K13) propeller domain. We found that 12.1% (8/66) of clinical P. falciparum isolates from Huye district, Rwanda, exhibited K13 mutations, including R561H, a validated resistance marker. K13 mu...

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Detalhes bibliográficos
Publicado no:Emerg Infect Dis
Main Authors: Bergmann, Clara, van Loon, Welmoed, Habarugira, Felix, Tacoli, Costanza, Jäger, Julia C., Savelsberg, Darius, Nshimiyimana, Fabian, Rwamugema, Elias, Mbarushimana, Djibril, Ndoli, Jules, Sendegeya, Augustin, Bayingana, Claude, Mockenhaupt, Frank P.
Formato: Artigo
Idioma:Inglês
Publicado em: Centers for Disease Control and Prevention 2021
Assuntos:
Dispatch
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7774571/
https://ncbi.nlm.nih.gov/pubmed/33350925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3201/eid2701.203527
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