Increase in Kelch 13 Polymorphisms in Plasmodium falciparum, Southern Rwanda

Artemisinin resistance in Plasmodium falciparum is associated with nonsynonymous mutations in the Kelch 13 (K13) propeller domain. We found that 12.1% (8/66) of clinical P. falciparum isolates from Huye district, Rwanda, exhibited K13 mutations, including R561H, a validated resistance marker. K13 mu...

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Dades bibliogràfiques
Publicat a:Emerg Infect Dis
Autors principals: Bergmann, Clara, van Loon, Welmoed, Habarugira, Felix, Tacoli, Costanza, Jäger, Julia C., Savelsberg, Darius, Nshimiyimana, Fabian, Rwamugema, Elias, Mbarushimana, Djibril, Ndoli, Jules, Sendegeya, Augustin, Bayingana, Claude, Mockenhaupt, Frank P.
Format: Artigo
Idioma:Inglês
Publicat: Centers for Disease Control and Prevention 2021
Matèries:
Dispatch
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7774571/
https://ncbi.nlm.nih.gov/pubmed/33350925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3201/eid2701.203527
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