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Interfacially Engineered Pyridinium Pseudogemini Surfactants as Versatile and Efficient Supramolecular Delivery Systems for DNA, siRNA, and mRNA

This article presents the synthesis, self-assembly, and biological activity as transfection agents for pDNA, siRNA, and mRNA of novel pyridinium pseudogemini surfactants, interfacially engineered from the most efficient gemini surfactants and lipids generated in our amphiphile research program. Form...

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Detalhes bibliográficos
Publicado no:ACS Appl Mater Interfaces
Main Authors: Satyal, Uttam, Draghici, Bogdan, Dragic, Lisa L., Zhang, Qiangnan, Norris, Kyle W., Madesh, Muniswamy, Brailoiu, Eugen, Ilies, Marc A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7774514/
https://ncbi.nlm.nih.gov/pubmed/28809098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsami.7b07066
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