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Modulation of pyridinium cationic lipid-DNA complex properties by pyridinium gemini surfactants and its impact on lipoplex transfection properties

The study presents the effects of blending a cationic gemini surfactant into cationic lipid bilayers and its impact towards plasmid DNA compaction and delivery process. Using nanoDSC, dynamic light scattering, zeta potential and electrophoretic mobility measurements, together with transfection (2D-...

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Detalhes bibliográficos
Main Authors: Sharma, Vishnu Dutt, Lees, Julia, Hoffman, Nicholas E., Brailoiu, Eugen, Madesh, Muniswamy, Wunder, Stephanie L., Ilies, Marc A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031282/
https://ncbi.nlm.nih.gov/pubmed/24377350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp4005035
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