Effect of Capivasertib in Patients With an AKT1 E17K-Mutated Tumor: NCI-MATCH Subprotocol EAY131-Y Nonrandomized Trial

IMPORTANCE: In the National Cancer Institute Molecular Analysis for Therapy Choice (NCI-MATCH) trial, agents targeting genetic tumor abnormalities are administered to patients. In the NCI-MATCH subprotocol EAY131-Y trial, patients with an AKT1 E17K-mutated metastatic tumor received the pan-AKT inhib...

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Detaylı Bibliyografya
Yayımlandı:JAMA Oncol
Asıl Yazarlar: Kalinsky, Kevin, Hong, Fangxin, McCourt, Carolyn K., Sachdev, Jasgit C., Mitchell, Edith P., Zwiebel, James A., Doyle, L. Austin, McShane, Lisa M., Li, Shuli, Gray, Robert J., Rubinstein, Larry V., Patton, David, Williams, Paul M., Hamilton, Stanley R., Conley, Barbara A., O’Dwyer, Peter J., Harris, Lyndsay N., Arteaga, Carlos L., Chen, Alice P., Flaherty, Keith T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Medical Association 2020
Konular:
Original Investigation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7774047/
https://ncbi.nlm.nih.gov/pubmed/33377972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2020.6741
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