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Age-Dependent Activation and Neuronal Differentiation of Lgr5+ Basal Cells in Injured Olfactory Epithelium via Notch Signaling Pathway

Aging is an important factor affecting function of smell, leading to the degeneration of mature olfactory sensory neurons and inducing the occurrence of smell loss. The mammalian olfactory epithelium (OE) can regenerate when subjected to chemical assaults. However, this capacity is not limitless. In...

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Bibliografske podrobnosti
izdano v:Front Aging Neurosci
Main Authors: Li, Xuewen, Tong, Meimei, Wang, Li, Qin, Yumei, Yu, Hongmeng, Yu, Yiqun
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7773941/
https://ncbi.nlm.nih.gov/pubmed/33390928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2020.602688
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