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Age-Dependent Activation and Neuronal Differentiation of Lgr5+ Basal Cells in Injured Olfactory Epithelium via Notch Signaling Pathway

Aging is an important factor affecting function of smell, leading to the degeneration of mature olfactory sensory neurons and inducing the occurrence of smell loss. The mammalian olfactory epithelium (OE) can regenerate when subjected to chemical assaults. However, this capacity is not limitless. In...

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Bibliographische Detailangaben
Veröffentlicht in:Front Aging Neurosci
Hauptverfasser: Li, Xuewen, Tong, Meimei, Wang, Li, Qin, Yumei, Yu, Hongmeng, Yu, Yiqun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7773941/
https://ncbi.nlm.nih.gov/pubmed/33390928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2020.602688
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