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Pregnancy-induced humoral sensitization overrides T cell tolerance to fetus-matched allografts in mice

Immunological tolerance to semiallogeneic fetuses is necessary to achieving successful first pregnancy and permitting subsequent pregnancies with the same father. Paradoxically, pregnancy is an important cause of sensitization, resulting in the accelerated rejection of offspring-matched allografts....

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Suah, Ashley N., Tran, Dong-Kha V., Khiew, Stella H.W., Andrade, Michael S., Pollard, Jared M., Jain, Dharmendra, Young, James S., Yin, Dengping, Chalasani, Geetha, Alegre, Maria-Luisa, Chong, Anita S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7773355/
https://ncbi.nlm.nih.gov/pubmed/33393512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI140715
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