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Overcoming innate immune barriers that impede AAV gene therapy vectors
The field of gene therapy has made considerable progress over the past several years. Adeno-associated virus (AAV) vectors have emerged as promising and attractive tools for in vivo gene therapy. Despite the recent clinical successes achieved with recombinant AAVs (rAAVs) for therapeutics, host immu...
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| Pubblicato in: | J Clin Invest |
|---|---|
| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7773343/ https://ncbi.nlm.nih.gov/pubmed/33393506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI143780 |
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