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Polygenic risk scores in clinical psychology: Bridging genomic risk to individual differences
Genomewide association studies (GWAS) across psychiatric phenotypes have shown that common genetic variants generally confer risk with small effect sizes (OR<1.1) that additively contribute to polygenic risk. Summary statistics derived from large discovery GWAS can be used to generate polygenic r...
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| Publicado no: | Annu Rev Clin Psychol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7772939/ https://ncbi.nlm.nih.gov/pubmed/29579395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-clinpsy-050817-084847 |
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