Remodeling of whole-body lipid metabolism and a diabetic-like phenotype caused by loss of CDK1 and hepatocyte division

Cell cycle progression and lipid metabolism are well-coordinated processes required for proper cell proliferation. In liver diseases that arise from dysregulated lipid metabolism, hepatocyte proliferation is diminished. To study the outcome of CDK1 loss and blocked hepatocyte proliferation on lipid...

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Vydáno v:eLife
Hlavní autoři: Ow, Jin Rong, Caldez, Matias J, Zafer, Gözde, Foo, Juat Chin, Li, Hong Yu, Ghosh, Soumita, Wollmann, Heike, Cazenave-Gassiot, Amaury, Ong, Chee Bing, Wenk, Markus R, Han, Weiping, Choi, Hyungwon, Kaldis, Philipp
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2020
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7771968/
https://ncbi.nlm.nih.gov/pubmed/33345777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.63835
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