Phase I trial of intracerebral convection-enhanced delivery of carboplatin for treatment of recurrent high-grade gliomas

BACKGROUND: Carboplatin is a potent cytoreductive agent for a variety of solid tumors. However, when delivered systemically, clinical efficacy for the treatment of high grade gliomas is poor due to limited penetration across the blood-brain barrier (BBB). Direct intracerebral (IC) convection-enhance...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Wang, Joshua L., Barth, Rolf F., Cavaliere, Robert, Puduvalli, Vinay K., Giglio, Pierre, Lonser, Russell R., Elder, J. Bradley
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7771668/
https://ncbi.nlm.nih.gov/pubmed/33373402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0244383
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