Potent henipavirus neutralization by antibodies recognizing diverse sites on Hendra and Nipah virus receptor binding protein

Hendra (HeV) and Nipah (NiV) viruses are emerging zoonotic pathogens in the Henipavirus genus causing outbreaks of disease with very high case fatality rates. Here, we report the first naturally occurring human monoclonal antibodies (mAbs) against HeV receptor binding protein (RBP). All isolated mAb...

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Veröffentlicht in:Cell
Hauptverfasser: Dong, Jinhui, Cross, Robert W., Doyle, Michael P., Kose, Nurgun, Mousa, Jarrod J., Annand, Edward J., Borisevich, Viktoriya, Agans, Krystle N., Sutton, Rachel, Nargi, Rachel, Majedi, Mahsa, Fenton, Karla A., Reichard, Walter, Bombardi, Robin G., Geisbert, Thomas W., Crowe, James E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7771633/
https://ncbi.nlm.nih.gov/pubmed/33306954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.11.023
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