A Cross-Reactive Humanized Monoclonal Antibody Targeting Fusion Glycoprotein Function Protects Ferrets Against Lethal Nipah Virus and Hendra Virus Infection

BACKGROUND: Nipah virus (NiV) and Hendra virus (HeV) are zoonotic paramyxoviruses that cause severe disease in both animals and humans. There are no approved vaccines or treatments for use in humans; however, therapeutic treatment of both NiV and HeV infection in ferrets and non-human primates with...

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Bibliografiske detaljer
Udgivet i:J Infect Dis
Main Authors: Mire, Chad E, Chan, Yee-Peng, Borisevich, Viktoriya, Cross, Robert W, Yan, Lianying, Agans, Krystle N, Dang, Ha V, Veesler, David, Fenton, Karla A, Geisbert, Thomas W, Broder, Christopher C
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
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Supplement Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199785/
https://ncbi.nlm.nih.gov/pubmed/31686101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiz515
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