Antagonism of STAT1 by Nipah virus P gene products modulates disease course but not lethal outcome in the ferret model

Nipah virus (NiV) is a pathogenic paramyxovirus and zoononis with very high human fatality rates. Previous protein over-expression studies have shown that various mutations to the common N-terminal STAT1-binding motif of the NiV P, V, and W proteins affected the STAT1-binding ability of these protei...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Satterfield, Benjamin A., Borisevich, Viktoriya, Foster, Stephanie L., Rodriguez, Sergio E., Cross, Robert W., Fenton, Karla A., Agans, Krystle N., Basler, Christopher F., Geisbert, Thomas W., Mire, Chad E.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6853903/
https://ncbi.nlm.nih.gov/pubmed/31723221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53037-0
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы