Characterization of viral insulins reveals white adipose tissue-specific effects in mice

OBJECTIVE: Members of the insulin/insulin-like growth factor (IGF) superfamily are well conserved across the evolutionary tree. We recently showed that four viruses in the Iridoviridae family possess genes that encode proteins highly homologous to human insulin/IGF-1. Using chemically synthesized si...

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Bibliografiske detaljer
Udgivet i:Mol Metab
Main Authors: Chrudinová, Martina, Moreau, François, Noh, Hye Lim, Páníková, Terezie, Žáková, Lenka, Friedline, Randall H., Valenzuela, Francisco A., Kim, Jason K., Jiráček, Jiří, Kahn, C. Ronald, Altindis, Emrah
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7770979/
https://ncbi.nlm.nih.gov/pubmed/33220491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.101121
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