Intestinal stem cell-derived enteroids from morbidly obese patients preserve obesity-related phenotypes: Elevated glucose absorption and gluconeogenesis

OBJECTIVE: The mechanisms behind the efficacy of bariatric surgery (BS) for treating obesity and type 2 diabetes, particularly with respect to the influence of the small bowel, remain poorly understood. In vitro and animal models are suboptimal with respect to their ability to replicate the human in...

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Udgivet i:Mol Metab
Main Authors: Hasan, Nesrin M., Johnson, Kelli F., Yin, Jianyi, Baetz, Nicholas W., Fayad, Lea, Sherman, Vadim, Blutt, Sarah E., Estes, Mary K., Kumbhari, Vivek, Zachos, Nicholas C., Kovbasnjuk, Olga
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7770968/
https://ncbi.nlm.nih.gov/pubmed/33246140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.101129
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