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NGAL decreases E-cadherin-mediated cell-cell adhesion and increases cell motility and invasion through Rac1 in colon carcinoma cells

Expression of neutrophil gelatinase-associated lipocalin (NGAL)/lipocalin2, a recently recognized iron regulatory protein that bonds to matrix metalloproteinase 9 (MMP9), is increased in a spectrum of cancers including those of the colorectum. Using colon carcinoma cell lines stably transfected with...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Lab Invest
Hauptverfasser: Hu, Limei, Hittelman, Walter, Lu, Tao, Ji, Ping, Arlinghaus, Ralph, Shmulevich, Ilya, Hamilton, Stanley R., Zhang, Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7770608/
https://ncbi.nlm.nih.gov/pubmed/19308044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2009.17
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