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Rapid Suppression of Activated Rac1 by Cadherins and Nectins during De Novo Cell-Cell Adhesion

Cell-cell adhesion in simple epithelia involves the engagement of E-cadherin and nectins, and the reorganization of the actin cytoskeleton and membrane dynamics by Rho GTPases, particularly Rac1. However, it remains unclear whether E-cadherin and nectins up-regulate, maintain or suppress Rac1 activi...

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Detalles Bibliográficos
Main Authors: Kitt, Khameeka N., Nelson, W. James
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055898/
https://ncbi.nlm.nih.gov/pubmed/21412440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017841
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